The high mortality rate and the enormous socio-economic consequences of the COVID-19 virus epidemic require the immediate development of effective treatment methods. The main complication of coronavirus infection, leading to the development of a fatal outcome, is pneumonia, respiratory and multiple organ failure, which develop in some patients with COVID-19 infection.

An analysis of the clinical, laboratory, and pathoanatomical picture of COVID-19 virus damage according to the literature suggests that there is a presence in the pathogenesis of patients with chronic disseminated intravascular coagulation (chronic DIC) and intra- alveolar fibrinogenesis.

Prevention of these processes, early therapy using the systemic method of leech therapy (SMP) of hirudotherapy, which has about 30 types of therapeutic effects, including anticoagulant and thrombolytic effects, can prevent the development of severe, life-threatening complications.